ClbP Is a Prototype of a Peptidase Subgroup Involved in Biosynthesis of Nonribosomal Peptides

The pks genomic island of Escherichia coli encodes polyketide (PK) and nonribosomal peptide (NRP) synthases that allow assembly of a putative hybrid PK-NRP compound named colibactin that induces DNA double-strand breaks in eukaryotic cells. The pks-encoded machinery harbors an atypical essential pro...

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Detalhes bibliográficos
Main Authors: Dubois, Damien, Baron, Olivier, Cougnoux, Antony, Delmas, Julien, Pradel, Nathalie, Boury, Michèle, Bouchon, Bernadette, Bringer, Marie-Agnès, Nougayrède, Jean-Philippe, Oswald, Eric, Bonnet, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195562/
https://ncbi.nlm.nih.gov/pubmed/21795676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.221960
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