IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells

Immune cells are key regulators of neoplastic progression, which is often mediated through their release of cytokines. Inflammatory cytokines such as IL-6 exert tumor-promoting activities by driving growth and survival of neoplastic cells. However, whether these cytokines also have a role in recruit...

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Main Authors: Fisher, Daniel T., Chen, Qing, Skitzki, Joseph J., Muhitch, Jason B., Zhou, Lei, Appenheimer, Michelle M., Vardam, Trupti D., Weis, Emily L., Passanese, Jessica, Wang, Wan-Chao, Gollnick, Sandra O., Dewhirst, Mark W., Rose-John, Stefan, Repasky, Elizabeth A., Baumann, Heinz, Evans, Sharon S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2011
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195455/
https://ncbi.nlm.nih.gov/pubmed/21926464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44952
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