A ssDNA Aptamer That Blocks the Function of the Anti-FLAG M2 Antibody

Using SELEX (systematic evolution of ligands by exponential enrichment), we serendipitously discovered a ssDNA aptamer that binds selectively to the anti-FLAG M2 antibody. The aptamer consisted of two motifs (CCTTA and TGTCTWCC) separated by 2-3 bases, and the elimination of one or the other motif a...

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Bibliographic Details
Main Authors: Lakamp, Amanda S., Ouellette, Michel M.
Format: Artigo
Language:Inglês
Published: SAGE-Hindawi Access to Research 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195435/
https://ncbi.nlm.nih.gov/pubmed/22013507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/720798
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