Monoclonal antibodies to the thyrotropin receptor: implications for receptor structure and the action of autoantibodies in Graves disease.

Hybridoma cells have been obtained by fusing P3-NS1/1-Ag4-1 mouse myeloma cells with spleen cells from mice immunized with solubilized preparations of the thyrotropin receptor. Five clones were produced that secrete a monoclonal antibody whose binding to thyroid membranes is specifically inhibited b...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Yavin, E, Yavin, Z, Schneider, M D, Kohn, L D
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1981
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6265939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.5.3180
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