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Effects of Kynurenine Pathway Metabolites on Intracellular NAD(+) Synthesis and Cell Death in Human Primary Astrocytes and Neurons
The kynurenine pathway (KP) is a major route of L-tryptophan catabolism resulting in the production of the essential pyridine nucleotide nicotinamide adenine dinucleotide, (NAD(+)). Up-regulation of the KP during inflammation leads to the release of a number of biologically active metabolites into t...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Libertas Academica
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3195228/ https://ncbi.nlm.nih.gov/pubmed/22084582 |
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