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Impact of Granulocytes on the Antimicrobial Effect of Tedizolid in a Mouse Thigh Infection Model

Tedizolid (TR-700, formerly torezolid) is the active component of the new oxazolidinone prodrug tedizolid phosphate (TR-701). We had previously demonstrated that tedizolid possessed potent antistaphylococcal activity superior to that of linezolid in a neutropenic mouse thigh infection model (A. Loui...

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Détails bibliographiques
Auteurs principaux: Drusano, G. L., Liu, Weiguo, Kulawy, Robert, Louie, Arnold
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195040/
https://ncbi.nlm.nih.gov/pubmed/21911576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00502-11
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