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Functional Characterization of Tn4401, a Tn3-Based Transposon Involved in bla(KPC) Gene Mobilization

The carbapenemase gene bla(KPC), which is rapidly spreading worldwide, is located on a Tn3-based transposon, Tn4401. In a transposition-conjugation assay, Tn4401 was able to mobilize bla(KPC-2) gene at a frequency of 4.4 × 10(−6)/recipient cell. A 5-bp target site duplication was evidenced upon each...

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Detalhes bibliográficos
Main Authors: Cuzon, Gaelle, Naas, Thierry, Nordmann, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195030/
https://ncbi.nlm.nih.gov/pubmed/21844325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05202-11
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