Impact of Mutations Outside the V3 Region on Coreceptor Tropism Phenotypically Assessed in Patients Infected with HIV-1 Subtype B

HIV coreceptor tropism (CTR) testing is a prerequisite for prescribing a coreceptor antagonist. CTR is increasingly deduced by analyzing the V3 loop sequence of gp120. We investigated the impact of mutations outside V3 on CTR as determined by the enhanced-sensitivity Trofile assay (ESTA). Paired EST...

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Detalhes bibliográficos
Main Authors: Monno, Laura, Saracino, Annalisa, Scudeller, Luigia, Punzi, Grazia, Brindicci, Gaetano, Altamura, Maurantonio, Lagioia, Antonella, Ladisa, Nicoletta, Angarano, Gioacchino
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195025/
https://ncbi.nlm.nih.gov/pubmed/21876051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00743-11
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