Efficacy of Single Intravenous Injection of Peramivir against Influenza B Virus Infection in Ferrets and Cynomolgus Macaques

We evaluated the efficacy of a single intravenous dose peramivir for treatment of influenza B virus infection in ferrets and cynomolgus macaques in the present study. A single dose of peramivir (60 mg/kg of body weight) given to ferrets on 1 day postinfection with influenza B virus significantly red...

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Détails bibliographiques
Auteurs principaux: Kitano, Mitsutaka, Itoh, Yasushi, Kodama, Makoto, Ishigaki, Hirohito, Nakayama, Misako, Ishida, Hideaki, Baba, Kaoru, Noda, Takahiro, Sato, Kenji, Nihashi, Yoichiro, Kanazu, Takushi, Yoshida, Ryu, Torii, Ryuzo, Sato, Akihiko, Ogasawara, Kazumasa
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195024/
https://ncbi.nlm.nih.gov/pubmed/21844317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00412-11
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