Nelfinavir and Its Active Metabolite, Hydroxy-t-Butylamidenelfinavir (M8), Are Transferred in Small Quantities to Breast Milk and Do Not Reach Biologically Significant Concentrations in Breast-Feeding Infants Whose Mothers Are Taking Nelfinavir

Antiretroviral drugs cross from maternal plasma to breast milk and from breast milk to the infant in different concentrations. We measured concentrations of nelfinavir and its active metabolite (M8) in maternal plasma and breast milk from women and in dried blood spots collected from their infants a...

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Detalhes bibliográficos
Main Authors: Weidle, Paul J., Zeh, Clement, Martin, Amy, Lando, Richard, Angira, Frank, Osoga, Joseph, Ogindo, Paul, Girde, Sonali, Minniear, Timothy D., Thomas, Timothy K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195023/
https://ncbi.nlm.nih.gov/pubmed/21876052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05273-11
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