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Juxtaposition of Two Distant, Serine-Arginine-Rich Protein-Binding Elements Is Required for Optimal Polyadenylation in Rous Sarcoma Virus
The Rous sarcoma virus (RSV) polyadenylation site (PAS) is very poorly used in vitro due to suboptimal upstream and downstream elements, and yet ∼85% of viral transcripts are polyadenylated in vivo. The mechanisms that orchestrate polyadenylation at the weak PAS are not completely understood. It was...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3194969/ https://ncbi.nlm.nih.gov/pubmed/21849435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00721-11 |
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