Transient Inactivation of the Neonatal Ventral Hippocampus Permanently Disrupts the Mesolimbic Regulation of Prefrontal Cholinergic Transmission: Implications for Schizophrenia

These experiments determined the mesolimbic modulation of cortical cholinergic transmission in a neurodevelopmental model of schizophrenia. Mesolimbic–cholinergic abnormalities are hypothesized to contribute to the cognitive deficits seen in schizophrenia. Stimulation of NMDA receptors in nucleus ac...

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Detalhes bibliográficos
Main Authors: Brooks, Julie M, Sarter, Martin, Bruno, John P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194075/
https://ncbi.nlm.nih.gov/pubmed/21814184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.136
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