Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypes

BACKGROUND: Type I interferons (IFNs) exhibit direct antiviral effects, but also distinct immunomodulatory properties. In this study, we analyzed type I IFN subtypes for their effect on prophylactic adenovirus-based anti-retroviral vaccination of mice against Friend retrovirus (FV) or HIV. RESULTS:...

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Hlavní autoři: Bayer, Wibke, Lietz, Ruth, Ontikatze, Teona, Johrden, Lena, Tenbusch, Matthias, Nabi, Ghulam, Schimmer, Simone, Groitl, Peter, Wolf, Hans, Berry, Cassandra M, Überla, Klaus, Dittmer, Ulf, Wildner, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193818/
https://ncbi.nlm.nih.gov/pubmed/21943056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-75
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