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Culture supernatants of a stimulated T-cell line have helper activity that acts synergistically with interleukin 2 in the response of B cells to antigen.

Culture supernatants of an antigen-stimulated long-term alloreactive T cell line, C.C3.11.75, contain a T-cell-replacing factor (TRF) activity for the B-cell response to antigen. These same supernatants show little activity in the T-cell growth assay or the costimulator assay. TRF activity was assay...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Swain, S L, Dennert, G, Warner, J F, Dutton, R W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1981
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6787609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2517
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