Synthesis of Unsymmetrical 3,4-Diaryl-3-pyrrolin-2-ones Utilizing Pyrrole Weinreb Amides

A regiocontrolled synthesis of unsymmetrical 3,4-diaryl-3-pyrrolin-2-ones has been achieved in three steps from 1,2-diaryl-1-nitroethenes with pyrrole-2-carboxamides (pyrrole Weinreb amides) serving as the key linchpin intermediates. Two different methods for the preparation of the requisite nitroal...

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Bibliografiske detaljer
Main Authors: Greger, Jessica G., Yoon-Miller, Sarah J.P., Bechtold, Nathan R., Flewelling, Scott A., MacDonald, Jacob P., Downey, Catherine R., Cohen, Eric A., Pelkey, Erin T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193567/
https://ncbi.nlm.nih.gov/pubmed/21913662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2013516
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