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Cohesin Selectively Binds and Regulates Genes with Paused RNA Polymerase

BACKGROUND: The cohesin complex mediates sister chromatid cohesion and regulates gene transcription. Prior studies show that cohesin preferentially binds and regulates genes that control growth and differentiation, and that even mild disruption of cohesin function alters development. Here we investi...

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Main Authors: Fay, Avery, Misulovin, Ziva, Li, Jian, Schaaf, Cheri A., Gause, Maria, Gilmour, David S., Dorsett, Dale
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193539/
https://ncbi.nlm.nih.gov/pubmed/21962715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.08.036
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