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Ultraviolet light action spectra for neoplastic transformation and lethality of Syrian hamster embryo cells correlate with spectrum for pyrimidine dimer formation in cellular DNA.

Action spectra were determined for neoplastic transformation, production of pyrimidine dimers, and lethality in Syrian hamster embryo cells. Of wavelengths between 240 and 313 nm, the most effective were 265 and 270. The relative sensitivities per quantum for transformation, pyrimidine dimer product...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Doniger, J, Jacobson, E D, Krell, K, DiPaolo, J A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319349/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6941297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2378
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