Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals

The mitochondrion is essential for energy metabolism and production of reactive oxygen species (ROS). In intact cells, respiratory mitochondria exhibit spontaneous “superoxide flashes”, the quantal ROS-producing events consequential to transient mitochondrial permeability transition (tMPT). Here we...

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Detalhes bibliográficos
Main Authors: Fang, Huaqiang, Chen, Min, Ding, Yi, Shang, Wei, Xu, Jiejia, Zhang, Xing, Zhang, Wanrui, Li, Kaitao, Xiao, Yao, Gao, Feng, Shang, Shujiang, Li, Jing-Chao, Tian, Xiao-Li, Wang, Shi-Qiang, Zhou, Jingsong, Weisleder, Noah, Ma, Jianjie, Ouyang, Kunfu, Chen, Ju, Wang, Xianhua, Zheng, Ming, Wang, Wang, Zhang, Xiuqin, Cheng, Heping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193463/
https://ncbi.nlm.nih.gov/pubmed/21556035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.81
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