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Polyamines are necessary for the survival of human small-cell lung carcinoma in culture.

Many human small-cell lung carcinoma culture lines grow as multicellular aggregate spheroids, for which high L-dopa decarboxylase activity is a marker. During the initial cell aggregation and the exponential growth phase, there is a marked increase in ornithine decarboxylase activity and an accumula...

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Detalhes bibliográficos
Main Authors: Luk, G D, Goodwin, G, Marton, L J, Baylin, S B
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC319344/
https://ncbi.nlm.nih.gov/pubmed/6264474
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