Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice

Platelets play an essential role in hemostasis and atherothrombosis. Owing to their short storage time, there is constant demand for this life-saving blood component. In this study, we report that it is feasible to generate functional megakaryocytes and platelets from human embryonic stem cells (hES...

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Detalhes bibliográficos
Main Authors: Lu, Shi-Jiang, Li, Feng, Yin, Hong, Feng, Qiang, Kimbrel, Erin A, Hahm, Eunsil, Thon, Jonathan N, Wang, Wei, Italiano, Joseph E, Cho, Jaehyung, Lanza, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193430/
https://ncbi.nlm.nih.gov/pubmed/21221130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.8
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