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Lysine methylation of promoter-bound transcription factors and relevance to cancer
p53, NFκB, STAT3, and several other transcription factors are reversibly methylated on lysine residues by enzymes that also modify histones. The methylations of NFκB and STAT3 take place when they are bound to promoters, suggesting a more general model in which the binding of inducible transcription...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193425/ https://ncbi.nlm.nih.gov/pubmed/21151202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.174 |
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