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Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming

Genomic imprinting, an epigenetic gene-marking phenomenon that occurs in the germline, leads to parental-origin-specific expression of a small subset of genes in mammals. Imprinting has a great impact on normal mammalian development, fetal growth, metabolism and adult behavior. The epigenetic imprin...

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Detalhes bibliográficos
Main Authors: Li, Yufeng, Sasaki, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193417/
https://ncbi.nlm.nih.gov/pubmed/21283132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.15
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