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Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut

Ookinete invasion of the mosquito midgut is an essential step for the development of the malaria parasite in the mosquito. Invasion involves recognition between a presumed mosquito midgut receptor and an ookinete ligand. Here, we show that enolase lines the ookinete surface. An antienolase antibody...

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Bibliographic Details
Main Authors: Ghosh, Anil K., Coppens, Isabelle, Gårdsvoll, Henrik, Ploug, Michael, Jacobs-Lorena, Marcelo
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193258/
https://ncbi.nlm.nih.gov/pubmed/21949403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103657108
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