Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei

Known mechanisms of resistance to β-lactam antibiotics include β-lactamase expression, altered drug target, decreased bacterial permeability, and increased drug efflux. Here, we describe a unique mechanism of β-lactam resistance in the biothreat organism Burkholderia pseudomallei (the cause of melio...

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Bibliografiske detaljer
Main Authors: Chantratita, Narisara, Rholl, Drew A., Sim, Bernice, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, Amornchai, Premjit, Thanwisai, Aunchalee, Chua, Hui Hoon, Ooi, Wen Fong, Holden, Matthew T. G., Day, Nicholas P., Tan, Patrick, Schweizer, Herbert P., Peacock, Sharon J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193241/
https://ncbi.nlm.nih.gov/pubmed/21969582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111020108
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