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Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8
Degradation of nuclear proteins by the 26S proteasome is essential for cell viability. In yeast, the nuclear envelope protein Cut8 mediates nuclear proteasomal sequestration by an uncharacterized mechanism. Here we describe structures of Schizosaccharomyces pombe Cut8, which shows that it contains a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193221/ https://ncbi.nlm.nih.gov/pubmed/21976488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103617108 |
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