Aquaporin-3 positively regulates matrix metalloproteinases via PI3K/AKT signal pathway in human gastric carcinoma SGC7901 cells

BACKGROUND: matrix metalloproteinases (MMPs) are produced by tumor cells, so they may be associated with tumor progression including invasion, migration, angiogenesis and metastasis. Aquaporin-3 (AQP3) also plays a critical role in gastric cancer cell migration and proliferation. METHODS: In this st...

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Bibliographic Details
Main Authors: Xu, Hao, Xu, Yong, Zhang, Wenjie, Shen, Lizong, Yang, Li, Xu, Zekuan
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193167/
https://ncbi.nlm.nih.gov/pubmed/21943213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-86
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