Single-Molecule Measurements of Dissociation Rates and Energy Landscapes of Binary trans SNARE Complexes in Parallel versus Antiparallel Orientation

Interactions between synaptobrevin 2 (Sb2) and syntaxin 1A (Sx1A) can be readily isolated and studied with the use of force spectroscopy single-molecule measurements. We studied interactions between Sx1A and Sb2 in two different orientations (parallel and antiparallel) using four different terminus...

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Autores principales: Liu, Wei, Montana, Vedrana, Parpura, Vladimir, Mohideen, U.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2011
Materias:
Cellular Biophysics and Electrophysiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192972/
https://ncbi.nlm.nih.gov/pubmed/22004738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.019
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