Positive Feedback Loops for Factor V and Factor VII Activation Supply Sensitivity to Local Surface Tissue Factor Density During Blood Coagulation

Blood coagulation is triggered not only by surface tissue factor (TF) density but also by surface TF distribution. We investigated recognition of surface TF distribution patterns during blood coagulation and identified the underlying molecular mechanisms. For these investigations, we employed 1), an...

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Autori principali: Balandina, A.N., Shibeko, A.M., Kireev, D.A., Novikova, A.A., Shmirev, I.I., Panteleev, M.A., Ataullakhanov, F.I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2011
Soggetti:
Biological Systems and Multicellular Dynamics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192965/
https://ncbi.nlm.nih.gov/pubmed/22004734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.034
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