Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis.

We partially purified a preparation from Escherichia coli that proteolytically degrades the enzyme glutamine synthetase [L-glutamate:ammonia ligase (ADP-forming), EC 6.3.1.2]. The degradation is at least a two-step process. First, the glutamine synthetase undergoes an oxidative modification. This mo...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Levine, R L, Oliver, C N, Fulks, R M, Stadtman, E R
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1981
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6113590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2120
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