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Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice

Gβ5 is a divergent member of the signal-transducing G protein β subunit family encoded by GNB5 and expressed principally in brain and neuronal tissue. Among heterotrimeric Gβ isoforms, Gβ5 is unique in its ability to heterodimerize with members of the R7 subfamily of the regulator of G protein signa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Jian-Hua, Pandey, Mritunjay, Seigneur, Erica M., Panicker, Leelamma M., Koo, Lily, Schwartz, Owen M., Chen, Weiping, Chen, Ching-Kang, Simonds, William F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192915/
https://ncbi.nlm.nih.gov/pubmed/21883221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07457.x
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