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A Novel Core Genome-Encoded Superantigen Contributes to Lethality of Community-Associated MRSA Necrotizing Pneumonia
Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune modulation and severe systemic illnesses such as Staphylococcus aureus toxic shock syndrome. However, all known S. aureus SAgs are encoded by mobile genetic elements and are made by only a proportion of strains. Here...
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Główni autorzy: | , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Public Library of Science
2011
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192841/ https://ncbi.nlm.nih.gov/pubmed/22022262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002271 |
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