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Barriers to Diffusion in Dendrites and Estimation of Calcium Spread Following Synaptic Inputs

The motion of ions, molecules or proteins in dendrites is restricted by cytoplasmic obstacles such as organelles, microtubules and actin network. To account for molecular crowding, we study the effect of diffusion barriers on local calcium spread in a dendrite. We first present a model based on a di...

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Bibliographic Details
Main Authors: Biess, Armin, Korkotian, Eduard, Holcman, David
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192802/
https://ncbi.nlm.nih.gov/pubmed/22022241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002182
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