A new high-throughput method for simultaneous detection of drug resistance associated mutations in Plasmodium vivax dhfr, dhps and mdr1 genes

BACKGROUND: Reports of severe cases and increasing levels of drug resistance highlight the importance of improved Plasmodium vivax case management. Whereas monitoring P. vivax resistance to anti-malarial drug by in vivo and in vitro tests remain challenging, molecular markers of resistance represent...

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Hlavní autoři: Barnadas, Céline, Kent, David, Timinao, Lincoln, Iga, Jonah, Gray, Laurie R, Siba, Peter, Mueller, Ivo, Thomas, Peter J, Zimmerman, Peter A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192712/
https://ncbi.nlm.nih.gov/pubmed/21943242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-282
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