Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradation

BACKGROUND: The arcuate nucleus of the hypothalamus regulates food intake. Ankyrin repeat and SOCS box containing protein 4 (Asb-4) is expressed in neuropeptide Y and proopiomelanocortin (POMC) neurons in the arcuate nucleus, target neurons in the regulation of food intake and metabolism by insulin...

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Detalhes bibliográficos
Main Authors: Li, Ji-Yao, Chai, Biaoxin, Zhang, Weizhen, Wu, Xiaobin, Zhang, Chao, Fritze, Danielle, Xia, Zefeng, Patterson, Cam, Mulholland, Michael W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192677/
https://ncbi.nlm.nih.gov/pubmed/21955513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-95
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