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TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception

TRP vanilloid 2 (TRPV2) is a nonselective cation channel expressed prominently in medium- to large-diameter sensory neurons that can be activated by extreme heat (>52°C). These features suggest that TRPV2 might be a transducer of noxious heat in vivo. TRPV2 can also be activated by hypoosmolarity...

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Main Authors: Park, Una, Vastani, Nisha, Guan, Yun, Raja, Srinivasa N., Koltzenburg, Martin, Caterina, Michael J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192449/
https://ncbi.nlm.nih.gov/pubmed/21832173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1384-09.2011
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