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The Response of Muscle Protein Anabolism to Combined Hyperaminoacidemia and Glucose-Induced Hyperinsulinemia Is Impaired in the Elderly

Muscle mass declines with aging. Amino acids alone stimulate muscle protein synthesis in the elderly. However, mixed nutritional supplementation failed to improve muscle mass. We hypothesized that the failure of nutritional supplements is due to altered responsiveness of muscle protein anabolism to...

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Bibliographic Details
Main Authors: VOLPI, ELENA, MITTENDORFER, BETTINA, RASMUSSEN, BLAKE B., WOLFE, ROBERT R.
Format: Artigo
Language:Inglês
Published: 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192447/
https://ncbi.nlm.nih.gov/pubmed/11134097
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