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Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA

AIMS/HYPOTHESIS: An elevated lipid content within skeletal muscle cells is associated with the development of insulin resistance and type 2 diabetes mellitus. We hypothesised that in subjects with type 2 diabetes muscle malonyl-CoA (an inhibitor of fatty acid oxidation) would be elevated at baseline...

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Detalhes bibliográficos
Main Authors: Bell, J. A., Volpi, E., Fujita, S., Cadenas, J. G., Rasmussen, B. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192446/
https://ncbi.nlm.nih.gov/pubmed/16868746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-006-0362-9
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