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Antigen-specific human T-cell clones: development of clones requiring HLA-DR-compatible presenting cells for stimulation in presence of antigen.

A method for cloning soluble antigen-specific proliferating human T lymphocytes directly from peripheral blood cells of individuals recently primed with the antigen is described. The soluble antigen was keyhole limpet hemocyanin. After expansion in liquid culture, these cells were shown to be antige...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sredni, B, Volkman, D, Schwartz, R H, Fauci, A S
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1981
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319234/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6972044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.3.1858
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