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Identification of classical anaphylatoxin as the des-Arg form of the C5a molecule: Evidence of a modulator role for the oligosaccharide unit in human des-Arg(74)-C5a

A functionally active and potentially lethal fragment of the fifth component of complement (C5) is generated during complement activation in serum from animals of various species. This factor, termed the “classical” anaphylatoxin, was isolated from porcine serum and was identified chemically as the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gerard, Craig, Hugli, Tony E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319229/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940191/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.3.1833
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