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EP4 receptor stimulation down-regulates human eosinophil function
Accumulation of eosinophils in tissue is a hallmark of allergic inflammation. Here we observed that a selective agonist of the PGE(2) receptor EP4, ONO AE1-329, potently attenuated the chemotaxis of human peripheral blood eosinophils, upregulation of the adhesion molecule CD11b and the production of...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SP Birkhäuser Verlag Basel
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192285/ https://ncbi.nlm.nih.gov/pubmed/21365278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0642-5 |
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