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Characterization of PDZ domain-peptide interaction interface based on energetic patterns

PDZ domain is one of the abundant modular domains that recognize short peptide sequences to mediate protein-protein interactions. In order to decipher the binding specificity of PDZ domain, we analyzed the interactions between 11 mouse PDZ domains and 2387 peptides using a method called MIEC-SVM, wh...

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Detalhes bibliográficos
Main Authors: Li, Nan, Hou, Tingjun, Ding, Bo, Wang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192264/
https://ncbi.nlm.nih.gov/pubmed/21928318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23157
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