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Nanoparticles for targeting the infarcted heart

We report a nanoparticulate system capable of targeting the heart after myocardial infarction (MI). Targeting is based on overexpression of angiotensin II type 1 receptor (AT1) in the infarcted heart. Liposomes 142 nm in diameter were conjugated with a ligand specific to AT1. The nanoparticles were...

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Bibliographic Details
Main Authors: Dvir, Tal, Bauer, Michael, Schroeder, Avi, Tsui, Jonathan H., Anderson, Daniel G., Langer, Robert, Liao, Ronglih, Kohane, Daniel S.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192253/
https://ncbi.nlm.nih.gov/pubmed/21899318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl2025882
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