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Antigen-presenting cell function in induction of helper T cells for cytotoxic T-lymphocyte responses: evidence for antigen processing.

We demonstrate that splenic adherent cells (SACs) play an active role in the presentation of H-2Kk antigen for an alloreactive cytotoxic T-lymphocyte (CTL) response. If antigen is incubated with SACs for 12 hr, they will provide maximal stimulation and present the antigen in the context of their Ia...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Weinberger, O, Herrmann, S, Mescher, M F, Benacerraf, B, Burakoff, S J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6972042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.3.1796
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