Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9

BACKGROUND: M-phase phosphoprotein 8 (MPP8) was initially identified to be a component of the RanBPM-containing large protein complex, and has recently been shown to bind to methylated H3K9 both in vivo and in vitro. MPP8 binding to methylated H3K9 is suggested to recruit the H3K9 methyltransferases...

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Main Authors: Li, Jing, Li, Zhihong, Ruan, Jianbin, Xu, Chao, Tong, Yufeng, Pan, Patricia W., Tempel, Wolfram, Crombet, Lissete, Min, Jinrong, Zang, Jianye
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192050/
https://ncbi.nlm.nih.gov/pubmed/22022377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025104
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