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Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9

BACKGROUND: M-phase phosphoprotein 8 (MPP8) was initially identified to be a component of the RanBPM-containing large protein complex, and has recently been shown to bind to methylated H3K9 both in vivo and in vitro. MPP8 binding to methylated H3K9 is suggested to recruit the H3K9 methyltransferases...

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Detalhes bibliográficos
Main Authors: Li, Jing, Li, Zhihong, Ruan, Jianbin, Xu, Chao, Tong, Yufeng, Pan, Patricia W., Tempel, Wolfram, Crombet, Lissete, Min, Jinrong, Zang, Jianye
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192050/
https://ncbi.nlm.nih.gov/pubmed/22022377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025104
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