Protective Role of Akt2 in Salmonella enterica Serovar Typhimurium-Induced Gastroenterocolitis

The Salmonella effector protein SopB has previously been shown to induce activation of Akt and protect epithelial cells from apoptosis in vitro. To characterize the role of Akt2 in host defense against Salmonella enterica serovar Typhimurium infection, wild-type (WT) mice and mice lacking Akt2 (Akt2...

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Hlavní autoři: Kum, Winnie W. S., Lo, Bernard C., Yu, Hong B., Finlay, B. Brett
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191998/
https://ncbi.nlm.nih.gov/pubmed/21555401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01235-10
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