Increased Disease Severity of Parasite-Infected TLR2(−/−) Mice Is Correlated with Decreased Central Nervous System Inflammation and Reduced Numbers of Cells with Alternatively Activated Macrophage Phenotypes in a Murine Model of Neurocysticercosis

In a murine model for neurocysticercosis (NCC), intracranial inoculation of the helminth parasite Mesocestoides corti induces multiple Toll-like receptors (TLRs), among which TLR2 is upregulated first and to a relatively high extent. Here, we report that TLR2(−/−) mice displayed significantly increa...

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Bibliographische Detailangaben
Hauptverfasser: Gundra, Uma Mahesh, Mishra, Bibhuti B., Wong, Kondi, Teale, Judy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191989/
https://ncbi.nlm.nih.gov/pubmed/21482681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00920-10
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