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Contributions of Kv7-mediated potassium current to sub- and suprathreshold responses of rat layer II/III neocortical pyramidal neurons

After block of Kv1- and Kv2-mediated K(+) currents in acutely dissociated neocortical pyramidal neurons from layers II/III of rat somatosensory and motor cortex, the remaining current is slowly activating and persistent. We used whole cell voltage clamp to show that the Kv7 blockers linopirdine and...

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Bibliografiske detaljer
Main Authors: Guan, D., Higgs, M. H., Horton, L. R., Spain, W. J., Foehring, R. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191833/
https://ncbi.nlm.nih.gov/pubmed/21697446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00211.2011
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