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Combining angiotensin II blockade and renin receptor inhibition results in enhanced antifibrotic effect in experimental nephritis

The limited antifibrotic effect of therapeutic angiotensin blockade, the fact that angiotensin blockade dramatically elevates renin levels, and recent evidence that renin has an angiotensin-independent, receptor-mediated profibrotic action led us to hypothesize that combining renin receptor inhibiti...

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Detalhes bibliográficos
Main Authors: Zhang, Jiandong, Gu, Chunyan, Noble, Nancy A., Border, Wayne A., Huang, Yufeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191801/
https://ncbi.nlm.nih.gov/pubmed/21795644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00271.2011
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