Hollow spheroids beyond the invasive margin indicate the malignant potential of colorectal cancer

OBJECTIVE: Tumour budding formed by histologically undifferentiated cancer cells beyond the border of the tumour margin is associated with lymph node metastasis. However, hollow tumour nests, a possible histologically advanced phenotype of tumour budding, have not been discussed. We examined whether...

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Detalhes bibliográficos
Main Authors: Tamura, Koichi, Yokoyama, Shozo, Ieda, Junji, Takifuji, Katsunari, Hotta, Tsukasa, Matsuda, Kenji, Oku, Yoshimasa, Watanabe, Takashi, Nasu, Toru, Kiriyama, Shigehisa, Yamamoto, Naoyuki, Nakamura, Yasushi, Shively, John E, Yamaue, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2011
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191579/
https://ncbi.nlm.nih.gov/pubmed/22021784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2011-000179
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