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Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues.

Poly(dG-dC).poly(dG-dC) and poly(dG).poly(dC) were modified by treatment with N-acetoxy-N-2-acetylaminofluorene, and their conformations were examined by circular dichroism and susceptibility to nuclease S1 digestion. A sample of poly(dG-dC).poly(dG-dC) modified to an extent of 28% with acetylaminof...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Santella, R M, Grunberger, D, Weinstein, I B, Rich, A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1981
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319148/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262801/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.3.1451
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